%A Xuezhen FENG, Zhuanquan XIAO, Guorong FAN, Zongde WANG %T Synthesis and Antifungal Activity of Hydronopyl Gemini Quaternary Ammonium Salts %0 Journal Article %D 2021 %J Biomass Chemical Engineering %R 10.3969/j.issn.1673-5854.2021.02.007 %P 45-49 %V 55 %N 2 %U {http://www.bce.ac.cn/CN/abstract/article_1129.shtml} %8 2021-03-30 %X

Three novel hydronopylgemini quaternary ammonium salts, namely tetramethylene-1,4-bis-(hydronopyl dimethyl ammonium chloride)(2a), pentamethylene-1,5-bis-(hydronopyl dimethyl ammonium chloride)(2b) and hexamethylene-1,6-bis-(hydronopyl dimethyl ammonium chloride)(2c) were synthesized from hydronopyl dimethyl amine and three α, ω-dibromoalkanes, respectively. Their structures were characterized by NMR and MS. The inhibition activities of the target compounds against nine plant pathogens were evaluated by mycelium growth rate method. The results showed that the three compounds had excellent antifungal activity against the tested plant pathogens, and compound 2c had the best inhibitory effect, in which its inhibitory rates on Colletotrichum acutatu, Sphaeropsis sapinea, Fusicoccum aesuli, Phytophthora parasitica var.Nicotianae and Fusarium oxysporum were much higher than that of chlorothalonil at all concentrations(12.5-200 mg/L) tested.