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Biomass Chemical Engineering ›› 2020, Vol. 54 ›› Issue (5): 1-7.doi: 10.3969/j.issn.1673-5854.2020.05.001

• Research Report •     Next Articles

Antibacterial Activity of Dehydroabietyl Nitrogen Derivatives

Zhaolan ZHAI1,Pu LYU2,Ping ZHAO2,Zhanqian SONG1,Shibin SHANG1,Xiaoping RAO1,3,*()   

  1. 1. Institute of Chemical Industry of Forest Products, CAF; National Engineering Lab. for Biomass Chemical Utilization; Key Lab. of Chemical Engineering of Forest Products, National Forestry and Grassland Administration; Key Lab. of Biomass Energy and Material, Jiangsu Province; Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, Nanjing 210042, China
    2. Key Laboratory of State Forestry Administration for Highly-Efficient Utilization of Forestry Biomass Resources in Southwest China, Southwest Forestry University, Kunming 650224
    3. Research Institute of Forestry New Technology, CAF, Beijing 100091, China
  • Received:2019-09-16 Online:2020-09-30 Published:2020-09-29
  • Contact: Xiaoping RAO E-mail:rxping2001@163.com
  • Supported by:
    国家重点研发计划资助项目(2017YFD0600205)

Abstract:

The antibacterial activities of dehydroabietic acid(1), dehydroabietylamine(2), dehydroabietamide derivatives(3a-3m), dehydroabietylamine benzaldehyde Schiff base derivatives (4a-4i), against six different pathogenic fungi were studied by using plate counting method. The results showed the antibacterial activity of dehydroabietylamine was better than that of dehydroabietic acid, and the antibacterial activities of dehydroabietylamine benzaldehyde Schiff base derivatives were better than that of dehydroabietamide. And the dehydroabietylamine p-chlorosalicylaldehyde Schiff base(4d), dehydroabietylamine m-fluorobenzaldehyde Schiff base(4f), dehydroabietylamine p-fluorobenzaldehyde Schiff base(4g) and dehydroabietylamine p-chlorobenzaldehyde Schiff base(4h) showed strong antibacterial activities. The inhibitory rates of sample 4h against Botrytis cinerea, Fusarium solani and Alternaria brassicae at 180 mg/L were up to 100%, which were close to the positive control, Actinomycin. The antibacterial activities of samples 4d, 4f, 4g and 4h at mass concentrations of 11.25, 22.5, 45 and 90 mg/L against six different pathogenic fungi were further studied. All the samples showed excellent antibacterial activities against Botrytis cinerea and Alternaria brassicae at different mass concentrations. The inhibitory rates of sample 4f at 22.5 mg/L against six different pathogenic fungi were more than 95%, but the sample 4g at 22.5 mg/L showed the lowest inhibitory rate. And the sample 4h at 45 mg/L showed the highest antibacterial activities. The above results demonstrated that the substitution position and the type of the halogen atom on the benzene ring affected the antibacterial activity at different mass concentrations and the concentration of the optimum antibacterial activity.

Key words: rosin, dehydroabietic acid, pathogenic fungi, inhibitory rate

CLC Number: