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生物质化学工程 ›› 2020, Vol. 54 ›› Issue (5): 45-52.doi: 10.3969/j.issn.1673-5854.2020.05.007

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生物预处理技术在天然产物提取中的应用研究进展

曾维星1,程贤1,张笮晦2,3,毕良武1,*(),赵振东1   

  1. 1. 中国林业科学研究院 林产化学工业研究所; 生物质化学利用国家工程实验室; 国家林业和草原局林产化学工程重点实验室; 江苏省生物质能源与材料重点实验室; 江苏省林业资源高效加工利用协同创新中心, 江苏 南京 210042
    2. 广西中医药大学 药学院; 广西中药药效研究重点实验室, 广西 南宁 530200
    3. 广西庚源香料有限责任公司, 广西 东兴 538100
  • 收稿日期:2019-10-21 出版日期:2020-09-30 发布日期:2020-09-29
  • 通讯作者: 毕良武 E-mail:biliangwu@126.com
  • 作者简介:曾维星(1995-),男,江西宜春人,硕士生,研究方向为天然产物化学与利用
  • 基金资助:
    国家重点研发计划资助项目(2018YFD0600405);四川省院省校合作项目(2019YFSY0002);中国林科院林产化学工业研究所研究团队建设创新工程项目(LHSXKQ2)

Application Research Progress of Biological Pretreatment Technology in Extraction of Natural Products

Weixing ZENG1,Xian CHENG1,Zuohui ZHANG2,3,Liangwu BI1,*(),Zhendong ZHAO1   

  1. 1. Institute of Chemical Industry of Forest Products, CAF; National Engineering Lab. for Biomass Chemical Utilization; Key Lab. of Chemical Engineering of Forest Products, National Forestry and Grassland Administration; Key Lab. of Biomass Energy and Material, Jiangsu Province; Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, Nanjing 210042, China
    2. College of Pharmacy, Guangxi University of Chinese Medicine; Guangxi Key Laboratory of Efficacy Study on Chinese Materia Medica, Nanning 530200, China
    3. Guangxi GengYuan Flavor and Fragrance Co. Ltd., Dongxing 538100, China
  • Received:2019-10-21 Online:2020-09-30 Published:2020-09-29
  • Contact: Liangwu BI E-mail:biliangwu@126.com
  • Supported by:
    国家重点研发计划资助项目(2018YFD0600405);四川省院省校合作项目(2019YFSY0002);中国林科院林产化学工业研究所研究团队建设创新工程项目(LHSXKQ2)

摘要:

生物预处理技术运用于天然产物提取是借助微生物或生物酶的作用,在适当条件下对天然资源进行处理,破坏植物原料的细胞壁,促进天然产物释放到提取介质中,以提高分离效率,有助于保证天然产物活性。生物预处理技术按形式可以分为微生物发酵技术和生物酶处理技术。针对2种生物预处理技术的作用机制和应用进行综述,旨在为天然产物开发利用提供参考。

关键词: 生物预处理, 天然产物, 提取

Abstract:

Biological pretreatment technology is applied to the extraction of natural products by the action of microorganisms or biological enzymes. Under appropriate conditions, the cell walls of natural resources are decomposed, which promotes the release of natural products into the extraction medium. Therefore, the efficiency of extraction and the activity of natural products are improved. Biological pretreatment technology includes microbial fermentation technology and biological enzyme assisted technology. This paper reviews the mechanism and application of two biological pretreatment techniques, aiming at providing reference for the development and utilization of natural products.

Key words: biological pretreatment, natural products, extraction

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